Murine -Fluorouracil-Based Submyeloablation Model for …
Jul · This property of -FU has been previously used to condition the BM for BM engraftment in mice for the purpose of investigating the contribution of various immune populations to pregnancy ( ) However the -FU regimen used in these models consisted of a single -mg kg -FU dose which has been shown in other studies to …
-Fluorouracil Treatment Leads to Activation of Stem Cell …
Dec · Interestingly the BM niche activated by -FU exerted a distinct effect on normal and leukemic cells in a manner that it provide higher support on the primitive state …
Frontiers Replication stress increases mitochondrial …
Mar · Fanconi Anemia (FA) is an inherited bone marrow (BM) failure disorder commonly diagnosed during school age However in murine models disrupted function of FA genes leads to a much earlier decline in fetal liver hematopoietic stem cell (FL HSC) number that is associated with increased replication stress (RS) Recent reports have …
Focus Medical Technology Investigation of Endothelial …
Sep · Cai B Fan J Zeng M Zhang L Fu BM Adhesion of malignant mammary tumor cells MDA-MB- to microvessel wall increases microvascular permeability via degradation of endothelial surface glycocalyx J Appl Physiol () () - PMC free article Google Scholar Tarbell JM Cancel LM
Bingmei M Fu - Google Scholar
J Fan B Cai M Zeng Y Hao FG Giancotti BM Fu Annals of biomedical engineering - Effect of surface charge of immortalized mouse cerebral endothelial cell monolayer on transport of charged solutes W Yuan G Li BM Fu Annals of biomedical engineering -
SWEET as Sugar New Sucrose Effluxers in Plants - Cell …
Mar · Fanconi Anemia (FA) is an inherited bone marrow (BM) failure disorder commonly diagnosed during school age However in murine models disrupted function of FA genes leads to a much earlier decline in fetal liver hematopoietic stem cell (FL HSC) number that is associated with increased replication stress (RS) Recent reports have …
Role of heparan sulfate in mediating CXCL-induced …
Feb · GAGs are heterogeneous unbranched polysaccharides with high charge densities (Fu Tarbell Tarbell Ebong Tarbell Pahakis Weinbaum Tarbell Damiano ) The most prominent GAG in the vasculature is heparan sulfate (HS) accounts for of the total GAG usually is present in the endothelial glycocalyx …
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Mar · Fanconi Anemia (FA) is an inherited bone marrow (BM) failure disorder commonly diagnosed during school age However in murine models disrupted function of FA genes leads to a much earlier decline in fetal liver hematopoietic stem cell (FL HSC) number that is associated with increased replication stress (RS) Recent reports have …
The Role of Endothelial Surface Glycocalyx in …
Oct · Yen WY Cai B Zeng M Tarbell JM Fu BM () Quantification of the endothelial surface glycocalyx on rat and mouse blood vessels Microvasc Res () CrossRef CAS PubMed PubMed Central Google Scholar Yen W Cai B Yang J Zhang L Zeng M Tarbell JM Fu BM () Endothelial surface glycocalyx can …
Myeloid progenitor cluster formation drives …
May · Abstract The effect of -fluorouracil (-FU) pretreatment on human bone marrow (BM) progenitor stem cells and recovery of hematopoiesis after autologous marrow
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Feb · GAGs are heterogeneous unbranched polysaccharides with high charge densities (Fu Tarbell Tarbell Ebong Tarbell Pahakis Weinbaum Tarbell Damiano ) The most prominent GAG in the vasculature is heparan sulfate (HS) accounts for of the total GAG usually is present in the endothelial glycocalyx …
Ablation of Proliferating Marrow with ‐Fluorouracil Allows …
Jan · Abbreviations -FU -fluorouracil BM bone marrow Figure Figure Open in figure viewer PowerPoint Quantative analysis of -FU-treated BM implants measured by micro-CT (A) The comparison of bone volume (mm ) in mouse and rat BM cell implants † p at × in the mouse BM cell group
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Apr · Yu lon felt Fu Zan begin to awaken It needed a new companion The Jade Serpent knew that soon she would honor Freya s wishes and allow a worthy mortal to carry Fu Zan And she was becoming certain that it needed to be given to a hozen Fu Zan the Wanderer s Companion Part Four ""Give it to someone who loathes battle and loves …
Bingmei Fu The City College of New York
Fu BM "Transport across the Blood-Brain Barrier" in "Molecular Cellular and Tissue Engineering of the Vascular System" Edited by Bingmei M Fu and Neil Wright Springer () Zeng Y Zhang F Fu BM and Tarbell J "The role of endothelial surface glycocalyx in mechanosensing and transduction" in "Molecular Cellular and
Interleukin- interacts with interleukin- and other …
May · The response of normal and day- post--FU BM containing high numbers of more mature progenitors was also assessed We found IL- enhanced colony formation by lineage-restricted megakaryocytic and erythroid progenitors in the presence of IL- and IL- plus erythropoietin (Epo) respectively The sum of these results shows that IL- interacts
Membrane protein CAR promotes hematopoietic regeneration upon stress
At days after -FU injection the Lincells from the BM of CAR cKO mice were isolated and the Lincells were resuspended in viral supernatants (× cells mL) with mg mL polybrene and centrifuged at rpm for hours before culturing for hours in StemSpan (StemCell Technologies) in the presence of ng mL stem cell factor ng
Accelerated recovery of peripheral blood cell counts …
May · Abstract The effect of -fluorouracil (-FU) pretreatment on human bone marrow (BM) progenitor stem cells and recovery of hematopoiesis after autologous marrow
Recruitment of Stem and Progenitor Cells from the Bone …
May · Stem cells within the bone marrow (BM) exist in a quiescent state or are instructed to differentiate and mobilize to circulation following specific signals Matrix metalloproteinase- (MMP-) induced in BM cells releases soluble Kit-ligand (sKitL) permitting the transfer of endothelial and hematopoietic stem cells (HSCs) from the …
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Jan · Abbreviations -FU -fluorouracil BM bone marrow Figure Figure Open in figure viewer PowerPoint Quantative analysis of -FU-treated BM implants measured by micro-CT (A) The comparison of bone volume (mm ) in mouse and rat BM cell implants † p at × in the mouse BM cell group
Bingmei Fu The City College of New York
Fu BM "Transport across the Blood-Brain Barrier" in "Molecular Cellular and Tissue Engineering of the Vascular System" Edited by Bingmei M Fu and Neil Wright Springer () Zeng Y Zhang F Fu BM and …
An R‐Derived FlowSOM Process to Analyze Unsupervised …
Oct · In a second step we extended the concept to the concomitant FlowSOM analysis of MNBM together with Dg and follow-up (FU) BM patient samples stained with the same antibody panels Although examples of the application of FlowSOM to classical MFC can be found in the literature this approach stands out as a completely novel way …
Bingmei Fu NYSTEM - Government of New York
Fu BM Shen S Acute VEGF effect on solute permeability of mammalian microvessels in vivo Microvasc Res Jul () - Fu BM Chen B A model for the modulation of microvessel permeability by junction strands J Biomech Eng Oct () - Guo P Hillyard SD Fu BM A two-barrier compartment model for volume flow across
Delineating the effects of -fluorouracil and follicle-stimulating
Apr · To study the effect of FSH on BM cells in -FU-treated mice recombinant FSH ( IU Gonal F U Merck Serono Switzerland) was injected subcutaneously h after animals were treated with -FU BM was harvested after and days of FSH treatment and processed for various studies as already described
Bingmei Fu NYSTEM - Government of New York
May · Abstract The effect of -fluorouracil (-FU) pretreatment on human bone marrow (BM) progenitor stem cells and recovery of hematopoiesis after autologous marrow
Delineating the effects of -fluorouracil and follicle …
Apr · Both VSELs and HSCs were activated in response to the stress created by -FU and FSH enhanced hematopoietic recovery by at least h in -FU-treated mice VSELs are the most primitive pluripotent stem cells in BM that self-renew and give rise to HSCs under stress and HSCs further divide rapidly an …
Medidas de adaptación al cambio climático - Food …
May · The response of normal and day- post--FU BM containing high numbers of more mature progenitors was also assessed We found IL- enhanced colony formation by lineage-restricted megakaryocytic and erythroid progenitors in the presence of IL- and IL- plus erythropoietin (Epo) respectively The sum of these results shows that IL- interacts
A Murine -Fluorouracil-Based Submyeloablation …
May · Abstract The effect of -fluorouracil (-FU) pretreatment on human bone marrow (BM) progenitor stem cells and recovery of hematopoiesis after autologous marrow
ATF Prevents Stress-Induced Hematopoietic …
Oct · Protection of hematopoietic stem cells (HSCs) from exhaustion and effective regeneration of the HSC pool after bone marrow transplantation or irradiation therapy is an urgent clinical need Here we …
How I treat MDS and AML in Fanconi anemia
Jun · BM dysplasia especially in children warrants careful evaluation by a hematopathologist with expertise in inherited BMF and MDS AML predisposition syndromes Regarding cytogenetic abnormalities q gains and q deletions are easy to detect with a conventional BM karyotype whereas q gains and RUNX abnormalities at q …
Post--fluorouracil human marrow stem cell characteristics …
May · Abstract The effect of -fluorouracil (-FU) pretreatment on human bone marrow (BM) progenitor stem cells and recovery of hematopoiesis after autologous marrow
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Restrictions in the stem cell function of murine bone marrow …
The data obtained at and days posttransplantation indicated that under the best conditions assayed (d -FU BM expanded for days with IL- SCF) almost no change in the competitive repopulation ability of the grafts was produced However when analysis was delayed to days posttransplantation a twofold reduction in the stem cell
Effect of Aging and -Fluorouracil Treatment on …
Fu BM "Transport across the Blood-Brain Barrier" in "Molecular Cellular and Tissue Engineering of the Vascular System" Edited by Bingmei M Fu and Neil Wright Springer () Zeng Y Zhang F Fu BM and …
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Lymphatic vessels in bone support regeneration after injury
Jan · Quantification of lymphatic vessel density in these mice (n = ) ELISA quantification of PROX concentration in tibiae from -FU -FU I and sham mice (n = ) (E) Bone marrow (BM) cellularity number of LSK cells and HSCs in bones from radiation (R) and radiation along with SAR (I) inhibitor (R I)-treated mice
Delineating the effects of -fluorouracil and follicle …
Fu BM "Transport across the Blood-Brain Barrier" in "Molecular Cellular and Tissue Engineering of the Vascular System" Edited by Bingmei M Fu and Neil Wright Springer () Zeng Y Zhang F Fu BM and …
Recruitment of Stem and Progenitor Cells from the Bone …
May · MMP- Is Induced in BM Cells after BM Ablation (A and B) MMP- − − and MMP- mice received a single dose of -FU i v BM cells obtained at different time points after -FU injection were cultured in serum-free medium overnight BM cell supernatants were assayed for pro-MMP- by Western blot (A) and active MMP- by …